TABLE I.
Demographic characteristics, induced sputum differential count, median percentage area of red hue/airway macrophage for the healthy, eosinophilic bronchitis, and asthma groups
Healthy (n = 10) |
NAEB (n = 15) |
GINA class I (n = 8) |
GINA class II-III (n = 18) |
GINA class IV-V (n = 46) |
|
---|---|---|---|---|---|
Age (y), mean (SE) | 32 (5) | 48 (3) | 46 (7) | 55 (3) | 50 (2) |
Male sex, no. (%) | 5 (50) | 8 (53) | 4 (50) | 10 (56) | 24 (52) |
FEV1 (% predicted), mean (SE) | 106 (6) | 100 (3) | 94 (4) | 87 (5) | 78 (4) |
Induced sputum (%), median (range) | |||||
Eosinophils | 0.4 (0-2.5) | 8.3 (3.3-68) | 0.9 (0-33.5) | 1.1 (0.1-45.3) | 1.5 (0-90.5) |
Neutrophils | 40.7 (8.3-66.8) | 47.3 (8.75-82.7) | 20 (0.4-77.2) | 60.8 (5.0-95.0) | 54.4 (2-93.5) |
Macrophages | 51.4 (28.8-90) | 27 (06-84) | 76 (12.4-90.6) | 26.5 (3.5-78.5) | 25.9 (5.2-78.50) |
Lymphocytes | 1.2 (0-9.8) | 0.5 (0-2.2) | 0.2 (0-0.5) | 0.8 (0-2.0) | 0.8 (0-4.5) |
Percentage area of red hue/airway macrophage, median (IQR) | 2.1 (1.9-3.8) | 36.3 (14.3-40.7) | 2.0 (0.9-9.1) | 10.7 (3.0-38.7) | 28.0 (11.8-68.0) |
IQR, Interquartile range.