. Author manuscript; available in PMC: 2014 Apr 21.

Published in final edited form as: J Allergy Clin Immunol. 2008 Jun 24;122(2):335–341.e3. doi: 10.1016/j.jaci.2008.05.020

TABLE III. Univariate and multivariate correlation of airway structure and function in asthma.

	Postbronchodilator FEV₁ %		Bronchodilator response FEV₁ (%)			Methacholine PC₂₀
	Univariate analysis		Univariate analysis			(mg/mL) Univariate analysis
	3β	P value	β	P value	∞ β	β	P value	∞ β
RBM thickness (μm)	0.22	.18	−0.14	.40	x	0.16	.34	x
Percent ASM	0.20	.22	−0.53	.74	x	0.16	.93	x
Percent glands	−0.26	.10	0.10	.55	x	0.12	.50	x
Percent collagen 3 lamina propria	0.18	.92	−0.072	.69	x	0.05	.81	x
Lamina propria eosinophil cells/mm²	−0.09	.60	0.32	.048	*0.31; P = .013*	0.32	.06	x
Lamina propria neutrophil cells/mm²	0.20	.20	−0.064	.70	x	0.13	.45	x
Mast cells/mm² ASM	−0.03	.89	−0.024	.89	x	*−0.51*	*.004*	− 0.43 P < .0001

β, Standardized regression coefficient; ∞, stepwise linear regression model–adjusted standardized regression coefficient.

Significant values are in boldface and italics.