Wing 2005.
Methods | Computer‐generated, random‐number sequence in sealed, opaque envelopes. Participants randomly allocated to sequential study number to get either mifepristone or standard regimen of intravenous oxytocin. | |
Participants | 65 women with spontaneous prelabour rupture of membranes beyond 36 weeks of gestation, and cervical dilatation < 3 cm. | |
Interventions | Single dose of 200 mg mifepristone (N = 33) or IV oxytocin (N = 32). If labour has not started within 18 hours, labour was induced with oxytocin IV in the mifepristone group. | |
Outcomes | Obstetric, neonatal. | |
Notes | Previous CS excluded. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Low risk | Adequate: "randomly allocated to the computer generated random number sequence". |
Allocation concealment? | Low risk | Adequate: "treatment assignments were placed in opaque, concealed and sequentially numbered envelopes". |
Blinding? All outcomes | High risk | Neither the participants or the personnel were blinded to the treatment received. |
Incomplete outcome data addressed? All outcomes | Low risk | Adequate as all participants completed the study and none were excluded in data analysis. |
Free of selective reporting? | Low risk | Adequate as all outcomes were reported. |
Free of other bias? | Low risk | Study completed. |
CS: caesarean section h: hours IUGR: intrauterine growth retardation IV: intravenous