Table 2.
Three-colored fluorescent in situ hybridization of sperm samples collected from one seminoma patient at different time points: before operation, before radiotherapy (after operation) and after radiotherapy. [n (100%)]
| Total sperms (n) | Normal karyotype sperms | Null signal sperms | Aneuploidy | Diploid | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||||
| Chromosome 18 | Sex chromosome | 1818, XX | 1818, XY | 1818, YY | ||||||||
|
|
|
|||||||||||
| 18, X | 18, Y | 1818, X | 1818, Y | 18, XX | 18, XY | 18, YY | ||||||
| Before operation | 12678 | 6313 | 6201 | 101 | 10 (0.079) | 9 (0.071) | 16 (0.126) | 14 (0.110) | 12 (0.095) | 6 (0.047) | 5 (0.039) | 6 (0.047) |
| Before radiotherapy (after operation) | 13099 | 6519 | 6372 | 122 | 9 (0.069) ns | 13 (0.099) ns | 21 (0.163) ns | 22 (0.168) ns | 27 (0.206)* | 8 (0.061) ns | 5 (0.038) ns | 7 (0.053) ns |
| After radiotherapy | 15167 | 7451 | 7282 | 147 | 26 (0.171)†,‡ | 29 (0.191)†,‡ | 64 (0.422)†,‡ | 52 (0.343)†,‡ | 65 (0.429)†,‡ | 21 (0.138)†,‡ | 22 (0.145)†,‡ | 26 (0.171)†,‡ |
*
P<0.05 vs. pre-operation group.
ns: no statistical significance while compared with pre-operation group.
†
P<0.05 vs. pre-operation group.
‡
P<0.05 vs. after operation group.