Table 1.
Diagnostic value parameters of the two methods in diagnosing uterine pathology
| Sensitivity | Specificity | PPV | NPV | LR (+) | |
|---|---|---|---|---|---|
| Any pathology (n=198) | |||||
| TVU | 96.0 (91.9-98.1) | 13.8 (7.6-23.2) | 71.7 (65.8-77.0) | 60.0 (36.4-80.0) | 1.1 (1.0-1.2) |
| Hysteroscopy | 92.9 (88.2-95.9) | 41.4 (31.1-52.4) | 78.3 (72.4-83.3) | 72.0 (57.3-83.3) | 1.6 (1.3-1.9) |
| Combined | 100.0 (97.6-100.0) | 41.4 (31.1-52.4) | 79.5 (73.9-84.2) | 100.0 (88.0-100.0) | 1.7 (1.4-2.0) |
| Polyp (n=133) | |||||
| TVU | 54.9 (46.0-63.4) | 84.9 (77.9-90.0) | 76.0 (66.0-83.9) | 68.3 (61.0-74.7) | 3.6 (2.4-5.4) |
| Hysteroscopy | 82.0 (74.1-87.9) | 84.9 (77.9-90.0) | 82.6 (74.8-88.4) | 84.3 (77.4-89.5) | 5.4 (3.7-8.0) |
| Combined | 86.5 (79.2-91.6) | 78.9 (71.4-85.0) | 78.2 (70.5-84.4) | 87.0 (80.0-91.9) | 4.1 (3.0-5.6) |
| Polyp >1 cm (n=115) | |||||
| TVU | 55.7 (46.1-64.8) | 88.7 (81.9-93.2) | 80.0 (69.3-87.8) | 71.0 (63.6-77.5) | 4.9 (3.0-8.0) |
| Hysteroscopy | 86.1 (78.1-91.6) | 91.5 (85.3-95.3) | 89.2 (81.5-94.0) | 89.0 (82.4-93.3) | 10.1 (5.9-17.5) |
| Combined | 88.7 (81.1-93.6) | 85.1 (77.9-90.3) | 82.9 (74.9-88.9) | 90.2 (83.5-94.4) | 6.0 (4.0-8.9) |
| Atrophy (n=27) | |||||
| TVU | 18.5 (7.0-38.7) | 99.6 (97.5-100.0) | 83.3 (36.5-99.1) | 92.1 (88.1-94.9) | 47.8 (5.8-394.1) |
| Hysteroscopy | 66.6 (46.0-82.8) | 99.6 (97.5-100.0) | 94.7 (71.9-99.7) | 96.6 (93.5-98.3) | 172.0 (23.9-1238.6) |
| Combined | 70.4 (49.7-85.5) | 99.2 (96.9-99.9) | 90.5 (68.2-98.3) | 97.0 (93.9-98.6) | 90.8 (22.3-368.9) |
Numbers in parenthesis denotes 95% confidence intervals. TVU, transvaginal ultrasonography, PPV, positive predictive value; NPV, negative predictive value; LR (+), positive likelihood ratio.