Table 2. Association between LINE-1 methylation and bladder cancer risk in the SBC/EPICURO study.
| LINE-1 methylation (tertiles) | Cases, n | Controls, n | Crude OR | 95% CI | P-value |
|---|---|---|---|---|---|
| T1 (<56.68%) |
337 |
298 |
1.29 |
(1.02–1.62) |
0.03 |
| T2 (56.68–<58.65%) |
261 |
297 |
1.00 |
Reference |
|
| T3 (⩾58.65%) |
354 |
297 |
1.36 |
(1.08–1.70) |
0.008 |
|
LINE-1 methylation (tertiles) |
Cases,
n |
Controls,
n |
ORa |
95% CI |
P-value |
| T1 (<56.68%) |
335 |
296 |
1.26 |
(0.99–1.60) |
0.06 |
| T2 (56.68–<58.65%) |
260 |
297 |
1.00 |
Reference |
|
| T3 (⩾58.65%) | 351 | 296 | 1.33 | (1.05–1.69) | 0.02 |
Abbreviations: CI=confidence interval; OR=odds ratio.
a
Model adjusted for age, sex, region and smoking status.