Table 1. Response and survival in Capan-1 tumour-bearing mice treated with rucaparib.

Treatment	Complete regressions	Mice remaining at day 40
Vehicle control	0/10	3a
10 mg kg−1 i.p., d × 5 w × 6	1/10	6
50 mg kg−1 p.o., d × 5 w × 6	0/10	2
150 mg kg−1 p.o., d × 5 w × 6	1/10	5
150 mg kg−1 p.o., 1 × w × 6	3/10	7
150 mg kg−1 p.o., 3 × w × 6	1/10	5
150 mg kg−1 p.o., dx5 every 3w	1/10	5

Abbreviations: d=daily; w=weekly; × =times.

^aMice killed due to tumour burden as described in Materials and Methods.