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. Author manuscript; available in PMC: 2014 Apr 21.
Published in final edited form as: Cancer Hallm. 2013 Aug 1;1(2-3):67–76. doi: 10.1166/ch.2013.1007

Figure 1. Trends in relationships between expression patterns and functional significance of homeobox genes in tumors.

Figure 1

Homeobox genes that are expressed in embryonic tissues and are ‘reactivated’ in tumors (red) tend to have tumor-promoting properties. Homeobox genes whose expression is normally maintained in differentiated adult tissues but is down-regulated in tumors (green) often exhibit tumor-suppressive properties.