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. 2013 Sep 11;22(5):675–680. doi: 10.1038/ejhg.2013.199

Table 4. Haplotype meta-analysis in the ‘CE' and ‘All' sample. Association results are given for the case-control analysis and for both quantitative measurements, word-reading and spelling.

      Case–Control Word-readinga Spellinga
      ‘CE' sample ‘All' sample ‘CE' sample ‘All' sample ‘CE' sample ‘All' sample
SNP combination Haplotype Gene Z P Z P Z P Z P Z P Z P
rs917235-rs714939 GG MRPL19/C2ORF3 0.59 5.58 × 10−01 0.35 7.30 × 10−01 −0.88 3.79 × 10−01 −0.91 3.60 × 10−01 −0.3 5.58 × 10−01 −0.01 9.93 × 10−01
rs1000585-rs917235-rs714939 GGG MRPL19/C2ORF3 0.02 9.82 × 10−01 0.01 9.92 × 10−01 −1.52 1.29 × 10−01 −1.36 1.74 × 10−01 −0.12 9.82 × 10−01 0.54 5.92 × 10−01
rs917235-rs714939-rs6732511 GGC MRPL19/C2ORF3 0.21 8.33 × 10−01 0.35 7.28 × 10−01 −1.22 2.24 × 10−01 −0.95 3.40 × 10−01 0.67 8.33 × 10−01 1.08 2.80 × 10−01
rs793862-rs807701 AC DCDC2 0.88 3.81 × 10−01 1.24 2.15 × 10−01 0.37 7.09 × 10−01 −0.33 7.41 × 10−01 −1.24 3.81 × 10−01 −1.08 2.79 × 10−01

Nominal significant P-values <0.05 are depicted in bold, Bonferroni-corrected P-value is 0.00072 (=0.05/69).

Z defines the test statistic of the meta-analysis.

a

Only the dyslexia cases were analysed.