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. 2013 Sep 18;22(5):633–639. doi: 10.1038/ejhg.2013.214

Figure 4.

Figure 4

PC and Chol determination. Analysis of PC (a) and Chol (b) secretion, and PC–Chol correlation (c) in MDR3 wild-type, MDR3 p.Y403H and MDR3 p.L481R cells. Cells were incubated for 24 h at 37 °C in the absence (0 mM) or presence of 0.5 mM, or 1 mM or 3 mM NaTC. The values represent the mean±SE of five experiments performed in triplicate. Asterisks indicate values significantly different (Student's unpaired t-test) from control values (*P≤0.05 and **P≤0.01 versus 0 NaTC). Symbols (§) indicate significant differences between mutant and wild-type cells after the same NaTC stimulus (§P≤0.05 and §§P≤ 0.01 versus MDR3 WT at the same NaTC concentration).