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. 2014 Mar 31;111(15):5652–5657. doi: 10.1073/pnas.1321803111

Fig. 5.

Fig. 5.

Bcl-6 and Blimp-1 inversely regulate revision. (A) Vβ5 Tg WT (black diamonds) and Bcl-6−/− (gray circles) CD4 T cells from mLN of mixed fetal-liver chimeras were analyzed 16–19 wk postreconstitution for (B) % pre-Tfh and GC Tfh and (C) % revising and postrevision T cells. Data are representative of two independent groups of chimeras, totaling 11 mice. (D) mLN CD4 T cells from 15- to 24-wk-old Vβ5 Tg WT (black diamonds) and Blimp-1gfp/+ (gray squares) mice were analyzed for % revising and postrevision T cells. Data are from seven to eight mice per group in five independent experiments. *P < 0.05, **P < 0.01, ***P < 0.005.