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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Comp Neurol. 2013 Sep 1;521(13):2947–2965. doi: 10.1002/cne.23324

Figure 4.

Figure 4

Depletion of muscle ciliary neurotrophic factor receptor α (CNTFRα) does not affect muscle weight or nerve lesion induced muscle weight loss. As expected, sciatic nerve crush led to decreased weight of tibialis anterior (A), extensor digitorum longus (EDL; B), and soleus (C) muscles at both 14 and 21 days post lesion (DPL) (*P <0.002; main effect of lesion in two-way ANOVAs with side relative to lesion treated as a within-measure). However, muscle CNTFRα depletion had no effect on muscle weight or the lesion-induced atrophy in any of the muscles at either postlesion interval (all comparisons P >0.05; main effect of CNTFRα depletion and interaction in two-way ANOVAs described above). Means with SEM are presented. Numbers in bars indicate number of mice. Legend in C applies to all panels.