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Forest plots of *28/*28 vs *1/*1, outcome: neutropenia. (a) (Stratified analysis based on 5-FU or analogue): +5-FU, received 5-FU or an analogue; −5-FU, did not receive 5-FU or analogue. (b) (Stratified analysis based on IRI-dose): high IRI, received medium or high dose of IRI; low IRI, received low dose of IRI. CI, confidence intervals; FU, fluorouracil; I2, inconsistency index.
