Table 1.
Variable | All Subjects at Baseline |
Unilateral STN DBS | Staged Bilateral STN DBS | p-value | ||
---|---|---|---|---|---|---|
Mean ± SD | N | Mean ± SD | N | Mean ± SD | ||
Age at First Surgery | 59.9 ± 9.8 | 51 | 60.2 ± 9.5 | 28 | 59.3 ± 10.4 | 0.8421 |
Weight (kg) | 81.5 ± 19.9 | 48 | 86.0 ± 18.6 | 23 | 72.2 ± 18.8 | 0.0076* |
Total UPDRS | 71.3 ± 15.5 | 53 | 69.0 ± 14.4 | 27 | 75.9 ± 16.7 | 0.0883 |
UPDRS Part 1 | 2.6 ± 1.8 | 54 | 2.6 ± 1.6 | 27 | 2.7 ± 2.2 | 0.9273 |
UPDRS Part 2 ‘off’ | 24.3 ± 6.1 | 54 | 23.7 ± 5.8 | 27 | 25.6 ± 6.6 | 0.1940 |
UPDRS Part 2 ‘on’ | 8.8 ± 5.1 | 53 | 8.6 ± 4.9 | 27 | 9.3 ± 5.5 | 0.5833 |
UPDRS Part 3 ‘off’ | 36.6 ± 10.8 | 54 | 34.8 ± 9.8 | 28 | 40.0 ± 11.8 | 0.0645 |
UPDRS Part 3 ‘on’ | 12.7 ± 7.5 | 53 | 12.4 ± 6.9 | 28 | 13.3 ± 8.5 | 0.8312 |
UPDRS Part 4 | 8.2 ± 2.5 | 53 | 8.2 ± 2.5 | 27 | 8.2 ± 2.6 | 0.9632 |
Tremor Subscore | 6.8 ± 6.2 | 53 | 5.9 ± 4.9 | 27 | 7.4 ± 5.1 | 0.1770 |
Dyskinesia Subscore | 2.4 ± 2.0 | 53 | 2.6 ± 2.1 | 27 | 2.0 ± 1.7 | 0.3420 |
Asymmetry index | 0.4 ± 0.2 | 53 | 0.5 ± 0.2 | 28 | 0.3 ± 0.2 | 0.0047* |