Table 3.
Baseline (X±SD) |
24 Month (X±SD) |
p-value | ||
---|---|---|---|---|
Bilateral (N =28 ) | ||||
Total UPDRS | 75.9 ± 16.7 | 61.5 ± 12.9 | 0.0007* | |
Part 1 | 2.7 ± 2.2 | 2.9 ± 2.3 | 0.9098 | |
Part 2 OFF | 25.6 ± 6.6 | 17.2 ± 3.8 | 0.0076* | |
Part 2 ON | 9.3 ± 5.5 | 9.2 ± 3.0 | 0.9645 | |
Part 3 OFF | 40.0 ± 11.8 | 24.2 ± 9.8 | 0.0086* | |
Part 3 ON | 13.3 ± 8.5 | 13.7 ± 8.3 | 0.5196 | |
Part 4 | 8.2 ± 2.6 | 3.5 ± 1.7 | <0.0001* | |
Unilateral (N =54 ) | ||||
Total UPDRS | 69.0 ± 14.4 | 56.8 ± 15.5 | 0.0004* | |
Part 1 | 2.6 ± 1.6 | 3.3 ± 2.3 | 0.4489 | |
Part 2 OFF | 23.7 ± 5.8 | 20.0 ± 6.7 | 0.0325* | |
Part 2 ON | 8.6 ± 4.9 | 9.4 ± 6.4 | 0.1787 | |
Part 3 OFF | 34.8 ± 9.8 | 24.4 ± 8.9 | 0.0104* | |
Part 3 ON | 12.4 ± 6.9 | 12.4 ± 6.9 | 0.1250 | |
Part 4 | 8.2 ± 2.5 | 3.8 ± 1.4 | <0.0001* |