Table 2.
Biomarker | n | Geometric mean (95% confidence interval) | Lower limit of top quintile | Standard threshold used |
Above standard thresholdn (%) |
Sample 95% reference rangea (n) |
---|---|---|---|---|---|---|
GGT | 1023 | 33.3 (31.8–34.9) | 53 U/l | 51 U/l [16] | 219 (21.4) | 12.1–86.7 (57) |
AST | 1023 | 31.0 (30.1–31.9) | 39.3 U/l | 37 U/l [16] | 238 (23.3) | 18.7–55.7 (57) |
ALT | 1023 | 27.0 (26.1–27.9) | 39.7U/l | 41 U/l [16] | 190 (18.6) | 13.7–37.4 (57) |
CDT | 997 | 1.18 (1.12–1.26) | 2.2% | 1.3% [30] | 334 (33.5) | 0.40–3.50 (57) |
MCV | 1021 | 89.0 (88.7–89.4) | 93.5 fL | 100 fL [16] | 37 (3.6) | 71.9–98.0 (56) |
Among men with body mass index (BMI) <25 drinking over zero and fewer than 2 l of alcohol per year and with negative hepatitis B and C status. GGT = gamma-glutamyl transferase; AST = aspartate aminotransferase; ALT = alanine aminotransferase; CDT = carbohydrate-deficient transferrin; MCV = mean cell volume of erythrocytes.