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. 2013 Jul 5;108(9):1579–1589. doi: 10.1111/add.12251

Table 5.

Univariable analysis of association of alcohol drinking with top quintile biomarkers

Number GGT
AST
ALT
CDT
MCV
n % n % n % n % n %
Drink any beer, wine, spirits or surrogates (current; within the previous 12 months: previous; prior to the previous 12 months: never; life-long abstainer)
Never 8 1 12.5 2 25.0 5 62.5 0/8 0 0/8 0
Previous 127 5 3.9 19 15.0 13 10.2 1/123 0.81 12/127 9.5
Current 888 201 22.6 189 21.3 188 21.2 205/866 23.7 196/886 22.1
P2) <0.001 0.24 <0.001 <0.001 0.001
Frequency of consuming any alcohol in the previous 12 months
(Almost) never 135 6 4.4 21 15.6 18 13.3 1/131 0.8 12/135 8.9
1–3 days/month 326 45 13.8 49 15.0 55 16.9 40/318 12.6 41/325 12.6
1–2 days/week 341 85 24.9 69 20.2 70 20.5 73/332 22.0 78/341 22.9
3–4 days/week 135 44 32.6 42 31.1 38 28.2 54/133 40.6 46/135 34.1
5–6 days/week 64 17 26.6 18 28.1 14 21.9 26/61 42.6 19/64 29.7
Daily 21 10 47.6 11 52.4 11 52.4 12/21 57.1 11/20 55.0
P2) <0.001 <0.001 <0.001 <0.001 <0.001
Total amount of ethanol from beverages per year (l/year) in the previous 12 months
None 135 6 4.4 21 15.6 18 13.3 1/131 0.8 12/135 8.9
>0 and <2 189 22 11.6 25 13.2 29 15.3 20/184 10.9 21/188 11.2
2–4 206 38 18.5 32 15.5 31 15.1 31/200 15.5 28/206 13.6
5–9 194 54 27.8 38 19.6 38 19.6 49/191 25.7 50/194 25.8
10–19 166 47 28.3 52 31.3 54 32.5 44/161 27.3 43/166 25.9
20 or more 120 35 29.2 39 32.5 33 27.5 57/117 48.7 49/119 41.2
P2) <0.001 <0.001 <0.001 <0.001 <0.001

GGT = gamma-glutamyl transferase; AST = aspartate aminotransferase; ALT = alanine aminotransferase; CDT = carbohydrate-deficient transferrin; MCV = mean cell volume of erythrocytes.