Table 3.
Regions of interest that show a significant correlation between the BPT and FA in all DS participants, with and without dementia
| FA correlation–Brief praxis test in DS | ||||
|---|---|---|---|---|
| Frontal | Parietal | Temporal | Occipital | |
| Forceps-minor | 379 | 0 | 0 | 0 |
| IFOF-R | 25 | 32 | 0 | 21 |
| IFOF-R | 0 | 133 | 0 | 82 |
| Uncinate-L | 27 | 0 | 0 | 0 |
| Uncinate-R | 0 | 0 | 0 | 0 |
| Genu-CC | 140 | 0 | 0 | 0 |
| Ant_Thal_Rad-L | 83 | 4 | 0 | 1 |
| Ant_Thal_Rad-R | 0 | 0 | 0 | 0 |
| SLF-L | 0 | 0 | 0 | 0 |
| SLF-R | 0 | 3 | 0 | 0 |
| Cing_Cing_Gyr-R | 111 | 0 | 0 | 0 |
| Cing_Cing_Gyr-L | 0 | 0 | 0 | 0 |
| Body-CC | 269 | 29 | 0 | 0 |
| Cing_Hipp-L | 0 | 0 | 0 | 0 |
| Cing_Hipp-R | 0 | 6 | 0 | 0 |
| CS-L | 0 | 0 | 0 | 0 |
| CS-R | 0 | 0 | 0 | 0 |
| Splenium-CC | 0 | 520 | 0 | 3 |
| Forceps-major | 0 | 575 | 0 | 156 |
| ILF-L | 0 | 18 | 0 | 16 |
| ILF-R | 0 | 38 | 0 | 36 |
Summary of 1 mm3 voxels within major white matter fiber tracks (corresponding to red ROIs from Fig. 2). The number of voxels within each lobe of the brain is listed. Key: Ant_Thal_Rad, anterior thalamic radiations; BPT, Brief Praxis Test; CC, corpus callosum; Cing_Cing_Gyr, cingulum of cingulate gyrus; Cing_Hipp, cingulum of hippocampus, CS, corticospinal, DS, Down syndrome; FA, fractional anisotropy; IFOF, inferior frontal occipital fasciculus; ILF, inferior longitudinal fasciculus; L, left; R, right; SLF, superior longitudinal fasciculus.