FIGURE 1.
sIL-2RA serum levels in healthy controls and MS subjects. A, Longitudinal sIL-2RA measurements in healthy control subjects. Samples were obtained over a period of 12 mo. B, Longitudinal sIL-2RA measurements in MS subjects with relapsing-remitting disease course. Samples were obtained over a maximum period of 3 years. C, sIL-2RA measurement in 68 healthy control subjects vs 284 MS subjects. Difference between means was tested using a two-sample t test with unequal variance. A summary of demographic characteristics of study participants and storage duration of samples is given in Table I. The difference remained significant (p = 0.0001) after adjusting for age, gender, and sample storage duration (data not shown).