FIG. 4.

Connecting rod width and length control the kinetics and location of rupture. Dogbones of varying length (6, 9, 12 mm; n=16, 13, 14, respectively) (A) and varying width (300, 400, 600, 800 μm; n=7, 12, 12, 12, respectively) (B) were followed over time, and the proportion of intact dogbones was computed for each time point, resulting in the generation of Kaplan–Meier curves. For these curves, only breaks in the rod region were counted as ruptures; breaks in the toroid regions were censored. Log-rank p-values for pair wise comparisons for the effects of width and length on the rate of rupture were computed (C). The points of rupture of dogbones of varying width were marked to specific locations on maps of dogbones of varying length (D).