FIG. 7.

Morphological changes to three-ring microtissues as a function of time, obstacle shape, and position. Three-ring microtissues were formed in a series of molds with three obstacles, each in the shape of a post (P) or a cone (C). The left to right order of the obstacles is labeled. Change in tissue shape over time was quantified from time lapse images by mapping the edges (width) of the tissues along a line connecting the centers of the three obstacles. The white line shown in (A) is the center line. The stars in (C) indicate the edges of the tissue which were mapped. Scale bar in (F) is 500 μm. Color images available online at www.liebertpub.com/tea