Table 4.
Maximum Platelet Aggregation, Slope, Lag Time, and Area Under the Curve Induced by ADP 8 μM, After Incubation with Aqueous Extracts from (Skin and Seed) Pomace 1 mg/mL Obtained from Hybrids of Two (Middle and Late) Growing Periods
| Cultivars | Pomace | Lag time (sec) | Slope | Maximum aggregation % | Area under the curve |
|---|---|---|---|---|---|
| Middle | Rich in skin | 0.2±0.1 | 38±2.3 | 57±4.6** | 253±7.8* |
| Rich in seed | 0.2±0.1 | 28±15.6 | 31±5.6 | 142±15.7 | |
| Average | 0.2±0.1 | 33±11.3 | 44±15 | 197±61.8 | |
| Late | Rich in skin | 0.2±0.1 | 37±5.1 | 48±5.3** | 207±28.6* |
| Rich in seed | 0.2±0.1 | 32±9 | 27±3.5 | 125±20.8 | |
| Average | 0.2±0.1 | 34±7.4 | 37±11.8 | 166±49.3 | |
| Negative control (Saline 0.9%) | 0.2±0.1 | 71±6.0 | 80±2.7 | 385±23 | |
| Positive control (PGE1) | 3.4±2.4 | 4.7±1.0 | 3±1.8 | 8.9±10 | |
Platelet aggregation induced by ADP 8 μM and the measurements were performed 6 min after agonist was added. Values are average±standard deviation of five determinations.
Maximum aggregation average (%) of the different growing seasons showed significant differences compared with negative control (saline 0.9%) (P<.0001). *P<.05, **P<.001 between middle and late cultivars.