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(A) LPA significantly increases production of vascular endothelial growth factor (VEGF) by MSC in GM and OM+, which is mitigated by the addition of Ki16425 (n=4). However, (B) the addition of VEGF does not affect MSC survival under SD/H (n=6). *p<0.0001 versus control, **p<0.01 versus SD/H, #p<0.001 versus SD/H+25 μM LPA, and ***p<0.01 versus LPA(−).
