Table 4.

Post Hoc Analysis of Fractional Anisotropy, Axial Diffusivity, and Radial Diffusivity Changes in Recently Detoxified Alcohol-Dependent Patients Who Relapsed to Pre-Baseline Alcohol-Use Levels

DTI measure	Baseline n = 4	Follow-up n = 4	Test value	p-Value
Fractional anisotropy
Genu	0.27 ± 0.09	0.26 ± 0.09	t = 0.31	0.78
Body	0.38 ± 0.05	0.37 ± 0.06	t = 0.90	0.43
Splenium	0.42 ± 0.16	0.43 ± 0.15	t = 0.96	0.41
Axial diffusivity
Genu	1.02 ± 0.75	1.60 ± 0.74	t = 2.33	0.10
Body	2.16 ± 0.27	2.20 ± 0.26	t = 1.55	0.21
Splenium	2.18 ± 0.44	2.07 ± 0.37	t = 1.07	0.36
Radial diffusivity
Genu	0.62 ± 0.34	1.15 ± 0.31	t = 2.84	0.07
Body	1.50 ± 0.12	1.56 ± 0.18	t = 1.27	0.29
Splenium	1.58 ± 0.51	1.56 ± 0.37	t = 0.29	0.79

DTI, diffusion tensor imaging.