Table 3.
Pooled estimates of adjusted HRs (95% CI) for all-cause and cardiovascular mortality according to categories of eGFR and dipstick urinalysis for proteinuria
| Dipstick |
||||
|---|---|---|---|---|
| eGFR (ml/min/1.73 m2) | − | ± | + | ≥++ |
| all-cause mortality | ||||
| ≥105 | 1.35 (0.94 - 1.92) | 2.34 (1.17 - 4.69) | 2.59 (1.32 - 5.07) | 4.40 (2.79 - 6.93) |
| 90-104 | reference | 1.47 (1.09 - 2.00) | 1.88 (1.27 - 2.77) | 2.44 (1.53 - 3.89) |
| 75-89 | 0.81 (0.65 - 1.01) | 1.44 (1.31 - 1.57) | 1.69 (1.50 - 1.89) | 2.43 (1.94 - 3.04) |
| 60-74 | 0.81 (0.59 - 1.10) | 1.27 (1.17 - 1.37) | 1.53 (1.32 - 1.78) | 1.88 (1.56 - 2.25) |
| 45-59 | 0.94 (0.66 - 1.32) | 1.38 (1.06 - 1.78) | 1.71 (1.52 - 1.92) | 2.41 (1.77 - 3.29) |
| 30-44 | 1.47 (0.97 - 2.22) | 1.94 (1.26 - 2.98) | 2.35 (1.66 - 3.33) | 2.86 (1.88 - 4.36) |
| 15-29 | 2.30 (1.61 - 3.29) | 4.37 (2.29 - 8.36) | 3.21 (2.00 - 5.13) | 5.98 (3.59 - 9.97) |
| cardiovascular mortality | ||||
| ≥105 | 0.96 (0.72 - 1.29) | 2.13 (1.22 - 3.74) | 3.27 (1.50 - 7.09) | 3.70 (1.17 - 11.68) |
| 90-104 | reference | 1.88 (1.32 - 2.69) | 1.68 (0.82 - 3.43) | 3.63 (1.58 - 8.32) |
| 75-89 | 0.82 (0.69 - 0.97) | 1.78 (1.33 - 2.37) | 2.08 (1.40 - 3.09) | 2.38 (1.40 - 4.04) |
| 60-74 | 0.99 (0.84 - 1.17) | 1.43 (1.13 - 1.82) | 1.84 (1.15 - 2.95) | 2.01 (1.26 - 3.19) |
| 45-59 | 1.38 (1.16 - 1.65) | 1.89 (1.47 - 2.44) | 2.40 (1.73 - 3.33) | 2.67 (1.58 - 4.50) |
| 30-44 | 2.42 (1.92 - 3.05) | 2.99 (2.13 - 4.20) | 2.73 (1.83 - 4.08) | 3.06 (2.00 - 4.70) |
| 15-29 | 3.29 (1.72 - 6.31) | 4.25 (2.28 - 7.93) | 7.66 (1.24 - 47.22) | 5.72 (1.66 - 19.73) |
Adjusted for age, race, gender, CVD history, systolic blood pressure, diabetes, smoking, total cholesterol.
Abbreviations: eGFR: estimated glomerular filtration rate; CVD: cardiovascular disease.