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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2013 Dec 4;143(1):189–201. doi: 10.1007/s10549-013-2796-3

Figure 1. Cumulative risk of bone (A, C) or non-bone (B, D) metastasis according to the full model, including clinical factors and copy number imbalances, in the discovery dataset (A, B) and validation dataset (C, D).

Figure 1

Figure 1

We stratified patients into three risk groups based on the sum of the predicted linear hazard ratios (HRs) from the final multivariate model (see Materials and Methods). Patients with higher predicted linear HRs have a higher risk of developing bone or non-bone metastasis at a given time point. Note that the numbers shown do not add up to the total number of patients in each specific subgroup due to missing data for clinical factors or outcome (time-to-metastasis).