TABLE 1.

T. barophilus plasmids used and constructed in this study

Plasmids	Resistance	Parent plasmid	Description	Reference
pUD	Ampicillin			19
pUDH	Ampicillin, simvastatin	pUD	Cloning of HMG-CoA reductase-encoding gene in pUD	This work
pUFH	Ampicillin, simvastatin	pUDH	Replacement of pyrF (T. kodakarensis) by pyrF (T. barophilus)	This work
pUDH-1	Ampicillin, simvastatin	pUDH	Cloning of homologous regions flanking pyrF	This work
pUFH-1	Ampicillin, simvastatin	pUFH	Cloning of homologous regions flanking hisB	This work
pUFH-2	Ampicillin, simvastatin	pUFH	Cloning of homologous regions flanking TERMP_00005	This work
pUHH	Ampicillin, simvastatin	pUFH-2	Replacement of pyrF by hisB	This work