TABLE 2.
Characteristics of pKpQIL-like plasmid-harboring isolates and their E. coli DH10 transformants
| Isolatea | Species | STb | MIC (μg/ml)c |
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IPM | ERT | MEM | DOR | CTX | CAZ | CFP | ATM | TIC/CLA | SXT | GEN | AMK | TOB | CIP | LVX | DOX | TGC | CST | PMB | |||
| 13001 | K. pneumoniae | 258 | >8 | >4 | >8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | >4/76 | 2 | 32 | ≥16 | ≥4 | >8 | 4 | 0.5 | 0.5 | 1 |
| 15720 | K. pneumoniae | 258 | >8 | >4 | >8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | >4/76 | >16 | 32 | ≥16 | ≥4 | >8 | ≤2 | ≤0.25 | 0.5 | 1 |
| 26633 | K. pneumoniae | 234 | 8 | >4 | >8 | ≥4 | 8 | 8 | 4 | >16 | >128/2 | ≤0.5/9.5 | ≤1 | ≤4 | ≤1 | ≤0.25 | ≤1 | 4 | ≤0.25 | 0.5 | 1 |
| 28611 | K. pneumoniae | 258 | >8 | >4 | >8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | >4/76 | 2 | ≥64 | ≥16 | ≥4 | >8 | 4 | 0.5 | 0.5 | 1 |
| 30799 | K. pneumoniae | 258 | >8 | >4 | >8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | >4/76 | 4 | ≤4 | ≥16 | ≥4 | >8 | 8 | 0.5 | 0.5 | 1 |
| 28944 | E. aerogenes | — | >8 | >4 | >8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | ≤0.5/9.5 | ≤1 | ≤4 | ≤1 | ≤0.25 | ≤1 | 8 | 1 | 0.5 | 1 |
| 28960 | E. coli | 131 | 8 | >4 | >8 | ≥4 | >32 | 16 | ≥32 | >16 | >128/2 | >4/76 | ≤1 | ≤4 | 2 | ≥4 | >8 | >16 | 0.5 | 1 | 1 |
| 13001T | E. coli | — | 4 | 4 | 8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | ≤0.5/9.5 | ≤1 | ≤4 | ≤1 | ≤0.25 | ≤1 | ≤2 | ≤0.25 | 0.5 | 1 |
| 15720T | E. coli | — | 8 | >4 | 8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | ≤0.5/9.5 | 2 | ≤4 | ≤1 | ≤0.25 | ≤1 | ≤2 | ≤0.25 | 0.5 | 1 |
| 26633T | E. coli | — | 4 | 2 | 2 | 2 | 8 | 8 | 4 | >16 | >128/2 | ≤0.5/9.5 | ≤1 | ≤4 | ≤1 | ≤0.25 | ≤1 | ≤2 | ≤0.25 | ≤0.25 | ≤0.25 |
| 28611T | E. coli | — | 8 | >4 | 8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | ≤0.5/9.5 | ≤1 | ≤4 | ≤1 | ≤0.25 | ≤1 | ≤2 | ≤0.25 | 0.5 | 1 |
| 30799T | E. coli | — | 4 | 2 | 4 | 2 | 16 | 16 | 8 | >16 | >128/2 | ≤0.5/9.5 | ≤1 | ≤4 | ≤1 | ≤0.25 | ≤1 | ≤2 | ≤0.25 | 0.5 | ≤0.25 |
| 28944T | E. coli | — | 8 | >4 | 8 | ≥4 | >32 | >16 | ≥32 | >16 | >128/2 | ≤0.5/9.5 | ≤1 | ≤4 | ≤1 | ≤0.25 | ≤1 | ≤2 | ≤0.25 | 0.5 | 1 |
| 28960T | E. coli | — | 4 | 1 | 2 | 2 | >32 | >16 | 16 | >16 | >128/2 | ≤0.5/9.5 | ≤1 | ≤4 | ≤1 | ≤0.25 | ≤1 | ≤2 | ≤0.25 | 0.5 | 1 |
a
T, E. coli DH10B transformant.
b
—, not tested.
c
MIC values were determined using broth microdilution; resistance values are indicated in boldface. IPM, imipenem; MEM, meropenem; ERT, ertapenem; DOR, doripenem; CAZ, ceftazidime; CTX, cefotaxime; CFP, cefepime; ATM, aztreonam; TIC/CLA, ticarcillin/clavulanate; AMK, amikacin; GEN, gentamicin; TOB, tobramycin; DOX, doxycycline; CIP, ciprofloxacin; LVX, levofloxacin; SXT, trimethoprim-sulfamethoxazole; TGC, tigecycline; CST, colistin; PMB, polymyxin B.