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(A) Sensitivity of wild-type E. coli C600 and Mut1 to Mut4 to pyrrhocoricin. The MIC value was 5 μM for the wild-type bacteria, higher than 80 μM for Mut1, and higher than 640 μM for Mut2, Mut3, and Mut4. (B) Growth curve for wild-type E. coli C600 and highly resistant mutants Mut2 to Mut4.
