TABLE 5.
Conventional meta-analyses of the different risk factors for acquisition and transmission of carbapenem-resistant P. aeruginosaa
| Risk factor | No. of factors | Pooled OR (random effects) | 95% CI | Range of OR in individual studies | Risk of publication bias |
|||
|---|---|---|---|---|---|---|---|---|
| Egger | P value | Kendall's tau | P value | |||||
| Carbapenem use | 16 | 7.09 | 5.43–9.25 | 3.6–76.0 | 1.39 | 0.02 | 0.47 | 0.01 |
| Medical devices | 19 | 5.11 | 3.55–7.37 | 2.1–64.3 | 2.30 | <0.001 | 0.49 | 0.003 |
| Other antibiotic use | 19 | 3.56 | 2.52–5.03 | 0.3–43.7 | 1.49 | 0.06 | 0.38 | 0.02 |
| ICU admission | 8 | 3.02 | 1.62–5.61 | 1.1–13.3 | 2.96 | 0.002 | 0.07 | 0.90 |
| Quinolone use | 11 | 2.73 | 1.27–5.87 | 0.1–48.4 | 0.89 | 0.56 | 0.45 | 0.06 |
| Underlying disease | 13 | 2.44 | 1.23–4.84 | 0.1–25.0 | 1.34 | 0.06 | −0.05 | 0.77 |
| Vancomycin use | 3 | 2.10 | 1.42–3.09 | 1.8–2.9 | NC | NC | NC | NC |
| Patient characteristics | 13 | 1.46 | 1.22–1.75 | 1.0–13.9 | 2.02 | <0.001 | 0.56 | 0.007 |
| Length of hospital stay | 9 | 1.06 | 1.02–1.09 | 1.0–6.7 | 3.05 | 0.0003 | 0.56 | 0.04 |
OR, odds ratio; CI, confidence interval; NC, not calculated because there were too few strata.