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Activity of OSIP108 and analogues against biofilm formation of C. albicans
| OSIP108 or analogue | Peptide | BIC-2 (μM) | Fold change |
|---|---|---|---|
| OSIP108 | MLCVLQGLRE | 5.3 | |
| S-OSIP108 | ELRLVCMGQL | >100 | >20 |
| d-OSIP108 | MLCVLQGLRE (all d-amino acids) | 13.7 | 2.6 |
| [CYC1]OSIP108 | Cyclo-MLCVLQGLRE | >100 | >20 |
| [CYC2]OSIP108 | Cyclo-MLCVLQGLREGG | 36.0 | 6.8 |
| [CYC3]OSIP108 | Cyclo-MLCVLQGLREC | >100 | >20 |
