TABLE 2.
Association of ntr4Tv and ntr6Tv haplotypes
| ntr4Tv haplotypea |
ntr6Tv haplotype (no. of isolates positive) (resistant [n = 50], susceptible [n = 50]) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Referenceb |
G259A |
G427C |
A238T/G427C/T476C |
Total |
||||||
| R | S | R | S | R | S | R | S | R | S | |
| Reference | 4 | 24 | 6 | 2 | 3 | 4 | 2 | 0 | 15 | 30 |
| G76C/C213G | 0 | 0 | 0 | 1 | 5 | 3 | 5 | 1 | 10 | 5 |
| G76C/C213G/C318A | 0 | 3 | 0 | 0 | 10 | 9 | 13 | 1 | 23 | 13 |
| T152A/G208C | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 |
| Total | 6 | 29 | 6 | 3 | 18 | 16 | 20 | 2 | 50 | 50 |
a
The ntr4Tv haplotype is displayed vertically, and the ntr6Tv haplotype is displayed horizontally. Numbers refer to the specific counts of resistant and sensitive isolates where the combination of haplotypes is found.
b
Reference sequence refers to that found in the sequenced G3 isolate. R indicates metronidazole resistant (MLC ≥ 50 μg/ml), and S indicates metronidazole susceptible.