FIG 1.
Infection establishment in a mouse SSI model. (A) A 1-cm-long, full-thickness incision wound was created on the dorsal side of the mouse. Approximately 1 cm of silk suture infected with S. aureus (approximately 5 × 103 cells/cm of suture) was placed into the wound and secured in the skin by knotting. One single nylon suture was attached over the middle of the incision. (B) Viable counts of bacteria per wound were analyzed in the tissue homogenate at 1, 2, 4, 24, 48, 72, and 96 h postinfection (n = 5 mice per time point).