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Antimicrobial dose-response effect of PXL150 administered in an aqueous solution (A) or in 1.5% HPC gel (B) in a mouse SSI model. Treatment was applied at 2 h postinfection, and analysis of bacterial survival in wounds was performed at 2 h posttreatment (n = 5 to 7 mice per group). *, P < 0.05; **, P < 0.01. HPC, hydroxypropyl cellulose.
