TABLE 1.
M. bovis BCG gene | M. tuberculosis homologue | Predicted function | Fold change for ΔraaS strain vs WT or ΔraaScom strain (assay method)a |
Fold change for ΔraaScom vs WT (qRT-PCR) | |||
---|---|---|---|---|---|---|---|
WT (MA) | ΔraaScom (MA) | WT (qRT-PCR) | ΔraaScom (qRT-PCR) | ||||
bcg1278c | rv1218c | ABC transporter | 29.56 | 46.45 | 48.9 | 82.79 | −1.69 |
bcg1277c | rv1217c | ABC transporter | 21.14 | 34.86 | 33.00 | 62.95 | −1.81 |
bcg1276c | rv1216c | Methyltransferase | 8.13 | 12.10 | 13.97 | 25.37 | −1.81 |
bcg1275c | rv1215c | Peptidase | 2.50 | 3.00 | 2.15 | 1.95 | 1.09 |
drrC | drrC | ABC transporter | 2.07 | 2.09 | 2.00 | 1.26 | 1.59 |
bcg3553 | rv3489 | Hypothetical protein | −2.22 | 3.45 | −1.05 | −1.22 | 1.15 |
Fold change relative to the WT or ΔraaScom strain was determined by microarray (MA) or qRT-PCR.