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Comparison of growth of fluoroquinolone-resistant M. tuberculosis gyrA mutants and their sensitive progenitor in the presence and in the absence of antibiotics. (A) Gly88Cys; (B) Asp94Tyr; (C) Asp94Asn; (D) Asp94His; (E) Asp94Gly. For each culture, the optical density at 600 nm was measured daily in three independent experiments, and the average was plotted. MOX, moxifloxacin; OFL, ofloxacin. Error bars indicate standard deviations.
