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Binding of pneumococcal strains 2-D39 (A), 4-CDC (B) and 19F-2737 (C) lacking one or more Pht proteins to nasopharyngeal epithelial cells (Detroit 562) or lung epithelial cells (A549 and NCI-H292). wt, wild type. The panels summarize five different experiments. Significant differences (Student's paired t test) are indicated with asterisks: *, P < 0.05; **, P < 0.01; ***, P < 0.001.
