FIG 7.
IL-17A regulates the production of sIgA and participates in bacterial clearance induced by DnaJ-ΔA146Ply. (A and B) Antibody titers were measured in serum and saliva taken from animals intranasally immunized with DnaJ-ΔA146Ply. Data are means and standard errors of the means from four mice. (C and D) Groups of six mice were intranasally immunized with the indicated antigens and intranasally challenged 2 weeks after the third immunization with 19F/CMCC31693 (1 × 107 CFU). Nasopharynx and lung colonization of individual mice was determined at day 4 after challenge. Each dot represents one mouse. The horizontal lines indicate the median CFU per nasopharynx or lung. WT, wild-type mice. *, P < 0.05; ***, P < 0.001.