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C. neoformans infection in CARD9 KO mice. WT and CARD9 KO mice were infected intratracheally with C. neoformans. The lung/body weight ratio was measured and the number of live colonies in lungs was counted on day 14 after infection. Each column represents the mean and SD for eight mice. Experiments were repeated twice with similar results. *, P < 0.05.
