TABLE 2.
Population distribution of E. coli strains HS, Nissle, and E2348/69 (EPEC) or CFT073 (UPEC) within the small intestinal (jejunum), ileal, cecal, and colonic mucus layers
| Expt and location | Mean log10 CFU ± SEMa for E. coli strain: |
|||
|---|---|---|---|---|
| HS | Nissle | E2348/69 | CFT073 | |
| E2348/69 cocolonization | ||||
| Jejunumb | 4.7 ± 0.1 | 4.2 ± 0.7 | 4.2 ± 0.9 | |
| Ileum | 4.2 ± 0.1 | 3.8 ± 0.1 | 3.8 ± 0.2 | |
| Cecum | 6.1 ± 0.2 | 6.5 ± 0.2 | 5.8 ± 0.3 | |
| Colon | 6.0 ± 0.5 | 6.8 ± 0.1 | 6.4 ± 0.6 | |
| Fecesc | 6.9 ± 0.9 | 7.3 ± 0.7 | 6.3 ± 0.2 | |
| CFT073 cocolonization | ||||
| Jejunumb | 4.7 ± 0.3 | 2.8 ± 0.6 | 2.4 ± 0.3 | |
| Ileum | 3.9 ± 0.4 | 3.9 ± 0.7 | 3.5 ± 1.1 | |
| Cecum | 5.1 ± 0.2 | 5.4 ± 0.4 | 5.5 ± 0.6 | |
| Colon | 5.7 ± 0.2 | 4.8 ± 0.5 | 4.7 ± 0.7 | |
| Fecesc | 6.4 ± 0.1 | 6.1 ± 0.3 | 6.2 ± 0.5 | |
a
Data from sets of 3 mice. SEM, standard error of the mean.
b
Mucus taken from below the stomach to the proximal ileum.
c
Fecal counts are in CFU/gram of feces collected on the day of intestinal sampling, as described in the text.