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M. tuberculosis infects microglia. The microglial cell line BV2 (A and B) and primary microglia (C and D), isolated from the cortices of 1-day-old C57BL/6 neonates, were infected with M. tuberculosis at an MOI of 2:1 for 6 and 24 h. The arrows indicate the uptake of acid-fast bacilli by the microglial cells. Scale bars, 20 μm.
