TABLE 4.
Detection of rifampin and isoniazid drug resistance by culture-based drug susceptibility testing versus MTBDR line probe assay
| Drug and result | Culture-based DST results (n [%]) |
Total | |||
|---|---|---|---|---|---|
| Resistanta | Susceptible | M. tuberculosis negative | Not available | ||
| Rifampin MTBDR-Plus LPA results | |||||
| Resistant | 22 (91.7) | 12 (3.4) | 0 | 2 (5.1) | 36 |
| Susceptible | 0 | 248 (70.5) | 0 | 10 (25.6) | 258 |
| Indeterminate | 1 (4.2) | 20 (5.7) | 0 | 0 | 21 |
| M. tuberculosis negative | 1 (4.2) | 65 (18.5) | 223 (99.6) | 25 (64.1) | 314 |
| Not available | 0 | 7 (2.0) | 1 (0.4) | 2 (5.1) | 10 |
| Total | 24 (100.0) | 352 (100.0) | 224 (100.0) | 39 (100.0) | 639 |
| Isoniazid MTBDR-plus LPA results | |||||
| Resistant | 24 (70.6) | 3 (0.9) | 0 | 2 (4.8) | 29 |
| Susceptible | 4 (11.8) | 257 (75.8) | 0 | 12 (28.6) | 273 |
| Indeterminate | 1 (2.9) | 12 (3.5) | 0 | 0 | 13 |
| M. tuberculosis negative | 5 (14.7) | 60 (17.7) | 223 (99.6) | 26 (61.9) | 314 |
| Not available | 0 | 7 (2.1) | 1 (0.4) | 2 (4.8) | 10 |
| Total | 34 (100.0) | 339 (100.0) | 224 (100.0) | 42 (100.0) | 639 |
a
Nineteen specimens were RIF and INH resistant (MDR TB).