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Antiviral activity of mutant mA3s. ΔVif HIV-1 (a) or MLV (b) carrying luciferase vectors were produced and assayed as described in Materials and Methods. Infectivities (as measured by the ability to induce luciferase in 293-MCAT cells) were normalized to RT activities, and this ratio for the controls lacking mA3 was set at 100%. Results are presented as relative specific (Rel. Sp.) infectivities. Error bars represent standard deviations.
