TABLE 1.
Score | Avg. no. of cell types at various sites |
|||||||
---|---|---|---|---|---|---|---|---|
CD3+ |
CD4+ |
HLA-DR |
Langerin |
|||||
IEL | LP | IEL | LP | IEL | LP | IEL | LP | |
0 | <1 | <1 | 0–6 | 0–6 | <1 | <1 | ||
1 | 1–5 | 1–5 | <10 | <10 | 7–10 | 7–10 | 1–5 | 1–5 |
2 | 6–25 | 6–25 | 10–25 | 10–25 | 11–25 | 11–25 | 6–25 | 6–25 |
3 | >25 | >25 | >25 | >25 | >25 | >25 | >25 | >25 |
For objective scoring criteria were as follows. Numbers and distribution of cells in foreskin epithelium (intraepithelial lymphocytes [IEL]) and lamina propria (LP) were evaluated in 10 fields at ×400 magnification and assigned a score of 0 to 3 based on the indicated range.