TABLE 2.
Effects of a rad51Δ mutation on the GCR rates of rnh203Δ mutantsa
| Genotype | RDKY no., GCR rate (with 95% CI) (fold increase relative to GCR rate of wild type) |
|
|---|---|---|
| Wild type | rnh203Δ | |
| Wild type | 7239, 3.6 (1.9–14.0) × 10−10 (1) | 7209, 2.0 (0.0–8.9) × 10−10 (0.5) |
| rad51Δ | 7344, 3.5 (1.5–7.9) × 10−9 (10) | 7346, 3.7 (1.8–21.6) × 10−9 (10) |
| asf1Δ | 7211, 1.4 (0.1–2.4) × 10−8 (39) | 7213, 4.1 (0.2–16.5) × 10−8 (114) |
| asf1Δ rad51Δ | 7501, <1.9 (0.0–30.0) × 10−9 (5) | 7503, 2.6 (1.1–7.9) × 10−8 (72) |
| esc2Δ | 7248, 1.7 (1.0–2.7) × 10−8 (48) | 7250, 2.1 (1.1–6.4) × 10−7 (592) |
| esc2Δ rad51Δ | 7507, 1.9 (0.0–3.1) × 10−9 (5) | 7509, 1.0 (0.0–3.3) × 10−8 (27) |
| mph1Δ | 7286, 1.1 (0.6–5.6) × 10−9 (3) | 7288, <1.2 (0.0–2.8) × 10−9 (3) |
| mph1Δ rad51Δ | 7511, 9.9 (0.0–44.3) × 10−10 (3) | 7513, 2.3 (1.2–3.5) × 10−9 (6) |
| sgs1Δ | 7414, 6.9 (2.7–11.4) × 10−9 (19) | 7416, 7.6 (6.2–11.7) × 10−8 (211) |
| sgs1Δ rad51Δ | 7515, 1.4 (0.3–2.0) × 10−8 (39) | 7517, 2.3 (0.5–19.0) × 10−8 (64) |
a
All strains are isogenic to wild-type RDKY7239 (MATα ura3-52 leu2Δ1 trp1Δ63 his3Δ200 lys2ΔBgl hom3-10 ade2::hisG ade8 hxt13::URA3). 95% CI, 95% confidence interval.