TABLE 1.
Prevalences of hepatitis B surface antigen, hepatitis D antibodies, and hepatitis D RNA in cohorts from different western and central African countries
| Country | Sampling location (yr) | Cohort type | Cohort size (n) | HBV/HDV prevalence (no. of positive patients/total no. of patients [%]) |
HDV clade present (no. of that clade) | |||
|---|---|---|---|---|---|---|---|---|
| HBsAg | HDV Aba | HDV RNAb | HDV RNA/HBsAg | |||||
| Burkina Faso | Bobo-Dioulasso (2001) | Mothers | 370 | 60/370 (16.2) | 1/40 (2.5) | 0/1 (0) | 0/40 (0) | |
| Bobo-Dioulasso (2001) | Children | 424 | 52/424 (12.2) | 9/44 (20.5) | 0/9 (0) | 0/44 (0) | ||
| Bobo-Dioulasso, Houndé (2007) | Pregnant women | 337 | 49/337 (14.5) | 0/49 (0) | 0/49 (0) | |||
| Nigeria | Ibadan (1998) | HIV+ patients | 106 | 11/69 (15.9) | 3/11 (27.3) | 0/3 (0) | 0/11 (0) | |
| Lagos (2004) | HIV+ patients | 319 | 45/308 (14.6) | 3/45 (6.7) | 2/3 (66.7) | 2/45 (4.4) | 1 (1); 6 (1) | |
| Ibadan (2003) | Liver patients | 93 | 44/70 (62.9) | 3/44 (6.8) | 0/3 (0) | 0/44 (0) | ||
| Ibadan (2006) | Liver patients | 126 | 103/126 (81.7) | 1/78 (1.3) | 1/1 (100) | 1/78 (1.3) | 1 (1) | |
| Abuja, Nasarawa state (2006) | HBsAg+ | 330 | 330/330 (100) | 40/326 (12.3) | 15/40 (37.5) | 15/326 (4.6) | 1 (6); 5 (5); 6 (1) | |
| Chad | Military camp (2007) | Military personnel | 50 | 14/50 (28)c | 3/14 (21.4)c | 3/14 (21.4)c | 1 (3) | |
| Central African Republic | Bangui (2007) | Children | 81 | 35/79 (44.3) | 1/35 (2.9) | 0/1 (0) | 0/35 (0) | |
| Bangui (2009) | Liver patients | 37 | 14/29 (48.3) | 7/14 (50) | 5/7 (71.4) | 5/14 (35.7) | 1 (6)d | |
a
Prevalence among HBsAg-positive samples, excluding equivocal samples.
b
Prevalence among HBsAg-positive HDV Ab-positive samples.
c
Prevalence calculations based on HBV and HDV TaqMan PCR. Samples positive for at least one assay were considered HBV positive.
d
Includes one sample that was not tested for HBsAg and therefore not included in the previous columns.