TABLE 1.
Detailed comparison of microscopy, RDT, and LAMP for malaria parasite detection and species identification
Parasite(s) detected by microscopy, RDT, and LAMPa (no. of samples; n = 219 blood samples) | ||
---|---|---|
Microscopy | LAMP | RDT |
P. falciparum (16) | P. falciparum (14), negativeb (2) | P. falciparum (16) |
P. falciparum + P. vivax (1) | P. falciparum + P. vivax (1) | P. falciparum + P. vivax (1) |
P. vivax (52) | P. vivax (51), negativec (1) | P. vivax (52) |
P. malariae (1) | P. malariae (1) | Negatived (1) |
Negative (149) | Negative (149) | Negative (146), P. falciparume (2), P. vivaxf (1) |
Each row displays results obtained from identical blood samples. Discordant results between LAMP and RDT are shown in boldface.
Positive for P. falciparum by nested PCR.
Positive for P. vivax by nested PCR.
The RDT can detect only P. falciparum and P. vivax, and this sample was positive for P. malariae by nested PCR.
Negative for P. falciparum by nested PCR.
Negative for P. vivax by nested PCR.