TABLE 3.
Summary of bioassay data from fetal tissues
| Tissue | Values for mice inoculated with fetal tissuesa: |
|||
|---|---|---|---|---|
| PG1658/05 | PG1673/05 | PG1674/05 | PG1675/05 | |
| Placentomeb | 18/19 (16; 543 ± 17) | 19/20 (15; 545 ± 18) | 18/19 (15; 470 ± 27) | 20/20 (17; 500 ± 20) |
| Umbilical Cordc | 13/18 (13; 530 ± 18) | NDd | 0/20 | 0/20 |
| Mesenteric LNc | 3/10 (3; 630 ± 46) | 0/10 | 0/5 | 0/10 |
| Spleenc | 0/20 | 0/20 | 0/20 | 0/20 |
| Liverc | 0/20 | 0/19 | 0/20 | 0/19 |
| Allantoic fluid | 0/20 | 0/20 | 0/20 | 0/20 |
| Amniotic fluid | 0/20 | 0/20 | 0/19 | 0/20 |
a
Values indicate numbers of TSE-positive mice/mice analyzed. TSE-positive mice include clinically positive animals and mice which died intercurrently and were subsequently diagnosed as TSE positive by immunohistochemistry. The number of clinically positive mice and the incubation period in days (mean ± standard error of the mean [SEM]) are indicated in parentheses. Mice were monitored for 850 days.
b
Tissues diagnosed as TSE positive when examined with immunohistochemistry.
c
Tissues diagnosed as TSE negative when examined with immunohistochemistry.
d
ND, not done.