TABLE 3.
HSV-1 proteins that increase G1/S in Fucci cells
| Protein name | Subcellular localization | Category | Function | Fold increase | SD |
|---|---|---|---|---|---|
| UL56 | Nuclear | Uncharacterized | Unknown but reduces virulence | 2.1 | 0.22 |
| UL24 | Nuclear | Tegument | Localization of viral glycoproteins | 2.1 | 0.19 |
| ICP35 | Pancellular | Capsid assembly | Protease, interacts with major capsid protein (VP5) | 2.0 | 0.10 |
| ORF O | Cytoplasmic | Uncharacterized | Related to ORFP, antisense to 34.5 | 2.0 | 0.13 |
| UL26 | Nuclear | Capsid assembly | Maturation protease | 2.0 | 0.32 |
| UL42 | Nuclear | Replication | Processivity subunit of HSV DNA polymerase | 1.9 | 0.07 |
| UL32 | Cytoplasmic | Capsid assembly | Capsid transport to replication compartments | 1.9 | 0.21 |
| UL20.5 | Nuclear | Uncharacterized | Unknown | 1.9 | 0.35 |
| ICP34.5 | Pancellular | Tegument | Neurovirulence factor, immunomodulation | 1.9 | 0.28 |
| UL52 | Cytoplasmic | Replication | Part of helicase-primase complex | 1.8 | 0.19 |
| UL8.5 | Nuclear | Uncharacterized | Unknown | 1.8 | 0.29 |