FIG 1.

Host- and virus-derived peptides. Peptides composed of 10 amino acids derived from the glycoproteins of viruses and human pro-neuropeptide Y and peptide F were synthesized. (A) SARS-CoV spike (S) protein-derived peptide (amino acids 674 to 683); (B) EBOV-GP protein-derived peptide (amino acids 196 to 205); (C) NiV fusion protein (F₀)-derived peptide (amino acids 105 to 114); (D) HeV fusion protein (F₀)-derived peptide (amino acids 105 to 114); (E) human pro-neuropeptide Y (pro-NPY)-derived peptide (amino acids 34 to 43); (F) human peptide F-derived peptide (amino acids 1 to 10); (G) control MHV-S glycoprotein-derived peptide (amino acids 713 to 722). Arrows indicate the cathepsin L cleavage sites in the corresponding peptides.